Dons’ goalkeeper David Martin has fractured his hand.
A timescale for Martin’s absence has not yet been determined but he is set to see a specialist to ascertain the extent of the damage.
Elsewhere, winger Rob Hall will undergo an MRI scan after suffering a knee injury in training.
However, Karl Robinson has centre-back Joe Walsh and midfielder Jake Forster-Caskey available again for selection after recovering from hamstring and foot injuries respectively.
Robinson told MK Dons PlayerHD: “Losing Dave is a big blow to everybody. Dave has been excellent for us this season and there’s no doubt we are going to miss him.
“Cody came in as the number 2 but he’s the number 1 now and he has to take that opportunity. I’ve got tremendous faith in him – he’s a good young goalkeeper.
“Hally is a big loss too. He was training, changed direction and he felt something in his knee. There was no-one near him, not even in a competitive environment – it was a freak one.”
He added: “These are obviously two negatives but we are positive going into the game with Fulham – there is a vibrancy and buoyancy about the players.
“We are confident and ready for the game.”