The Dons returned to winning ways on Saturday, courtesy of a 2-0 victory over Yeovil Town at Huish Park.
Jordan Spence, Tom Flanagan and Grigg replaced George Baldock (ankle), Antony Kay (hamstring) and Dean Bowditch in the starting XI for the clash in Somerset. Recent recruit Carl Baker was named in the squad for the first time.
The Dons were the first to threaten in the fourth minute when Benik Afobe and Ben Reeves both saw efforts blocked in quick succession following a smart move down the left.
Karl Robinson’s side were looking impressive in the opening exchanges, but the hosts offered a brief warning when Aaron Martin glanced a header just wide from Simon Gillett’s free-kick on nine minutes.
A direct run from Powell almost brought about the opener three minutes later but, after beating three Yeovil players, the left-sided winger lifted his 20-yard effort over the top.
At the other end, James Hayter dragged a long-range effort past the post before Jordy Hiwula headed off target as the hosts pulled themselves back into the game midway through the first half.
The windy conditions were making things difficult for both sides which prompted a lull in proceedings, before Dele Alli tried to spark the fixture back into life with an effort which was deflected behind for a corner five minutes before the break.
The Dons turned up the pressure in the closing stages of the half and were unfortunate not to be playing against 10 men when Ben Nugent clearly palmed the ball away under pressure from Grigg – the referee however determined the defender wasn’t denying a goalscoring opportunity.
Hiwula was presented with a golden opportunity to give the Glovers the lead just 30 seconds into the second half, but the Manchester City loanee blazed high over the bar when well placed.
A minute later, David Martin produced a stunning save with his right leg to deny Hayter’s fierce effort finding the back of the net.
The Dons responded with two chances of their own shortly afterwards – Grigg forcing Jacob Kean into a finger-tip save before Afobe’s acrobatic effort landed on the roof of the net.
Ajay Leitch-Smith and Joel Grant were introduced for Hayter and James Berrett as Yeovil boss Gary Johnson tried to swing the game their way, but the hosts were dealt a major blow when Nugent was sent off after picking up his second yellow card for a foul of Grigg with 25 minutes remaining.
The Dons didn’t waste any time in making their numerical advantage count as Randall perfectly picked out Grigg, who took a touch before coolly firing the ball into the bottom left-hand corner on 69 minutes - his sixth goal of the season.
The dangerous Powell made it 2-0 on 85 minutes, picking the ball up 40-yards out, driving at the home defence and curling a fine effort into the right-hand corner.
Martin made sure the Dons left with the points and a clean sheet in the 89th minute, denying Hiwula from close range after he had been picked out by Grant.
Starting XI: Martin; Spence, McFadzean, Flanagan (Randall 33), Lewington (c); Potter (Baker 86), Alli; Reeves, Grigg (Carruthers 88), Powell; Afobe.
Unused subs: McLoughlin, Bowditch, Hitchcock.
Goals: Grigg (69), Powell (85).
Bookings: Potter, Reeves, Powell, Randall.
Attendance: 4,000 (337 Dons fans)