Karl Robinson makes one change to the side that beat AFC Wimbledon, with Zeli Ismail making his first start for the Club.
Ismail, who has featured twice from the bench since joining on loan from Wolves, replaces Dean Bowditch after the Dons no. 9 was deemed unfit after picking up a knock in the FA Cup win last Sunday.
Elsewhere, the starting XI remains unchanged with Ryan Lowe continuing to lead the line up-front with loanee Patrick Bamford still receiving treatment at his parent club Chelsea.
On the bench, winger Daniel Powell returns to the squad for the first time since the 2-2 draw with Shrewsbury Town.
Brentford: Moore, Forshaw, Craig, Dean, Douglas, Donaldson, Logan, Forrester, Diagouraga, Trotta, Bidwell.
Subs: Lee (GK), Saunders, Dallas, Hodson, Reeves, Hayes, Kiernan.
MK Dons (4-2-3-1): Martin; Otsemobor, Kay, Williams, Lewington (c); Gleeson, Potter; Ismail, Chadwick, Balanta; Lowe.
Subs: McLoughlin (GK), Kouo-Doumbe, MacDonald, Smith, Chicksen, Powell, Sekajja.
Referee: L Collins