MK Dons make their first ever journey to the Globe Arena thevening and will be going in search of their sixth straight Sky Bet League Two victory.
Paul Tisdale's side have enjoyed a 100 percent record over the last five matches and have moved into the automatic promotion places as a result of that form.
The Dons are enjoying their best run of results since 2015 but with fourth-place Mansfield Town just a point behind them, they know they must keep their foot firmly on the pedal.
Kick-off is at 7.45pm.
Morecambe head into this fixture having picked up an important three points against Forest Green Rovers last Saturday. The win over Forest Green pulled Jim Bentley's side eight points clear of the relegation zone.
Bentley is currently the longest-serving manager in the EFL. He took over back in 2011 and has since helped the Club maintain their status in the EFL.
Striker Kevin Ellison currently has six goals to his name, while Aaron Collins has also impressed since joining in February. The former Wolves forward has netted three times in five games since his arrival.
Elsewhere, Rhys Oates has scored in six separate occasions, with defender Jordan Cranston finding the net three times this season.
LAST TIME OUT!
MK Dons moved into the Sky Bet League Two automatic promotion on Saturday following a 3-1 win against Macclesfield Town.
Paul Tisdale's men fell behind at Moss Rose but struck back just before half-time through David Wheeler, who scored his first goal for the Club.
In the second half, Callum Brittain fired home his first of the campaign to put the Dons ahead and then Kieran Agard put the seal on a fine afternoon's work with a looping header.
Morecambe, meanwhile, were 3-0 winners over Forest Green Rovers. Goals from Rhys Oates, Aaron Collins and Alex Kenyon secured the victory for Jim Bentley's side.
Paul Tisdale: "It’s about the next game for us. Often clichés have a meaning, and at this point, it's the right thing to say.”
“We'll go back, get into our routine and go again on Tuesday.”
Jim Bentley: "We hadn't won at home for a while and we had lost the last two. We shouldn’t have lost the (Yeovil) game but we’ve bounced back in front of our own fans.
“We have another big game on Tuesday (against MK Dons) and we have to try and back it up with another win.”
Paul Tisdale did not hold a pre-match press conference ahead of tonight's clash but when he addressed the media at the weekend, he didn't state he had any fresh injury concerns from the win.
He is, therefore, expected to field a similar squad with Jordan Moore-Taylor, Baily Cargill, Mathieu Baudry and George Williams still sidelined.
Morecambe are without defender Jordan Cranston, who will serve the second game of his two-match ban for collecting 10 yellow cards.
Striker A-Jay Leitch-Smith remains on the sidelines with a hamstring injury.
Ross Joyce will take charge of tonight's affair. It'll be the second time he's overseen an MK Dons game this season.
He most recently run the rule over a Dons game back in October - MK Dons' 2-0 win over Port Vale.
Mr Joyce has officiated 37 matches this campaign, producing a total of 134 yellow cards and showing just the one red.
His assistant referees are Graeme Fyvie and Ian Dudley while the fourth official is Gareth Mellor.
HEAD TO HEAD!
This will be only the fourth between MK Dons and Morecambe - with it being the first to take place at the Globe Arena.
The last time the Dons faced Morecambe away from home was in 2007, with the game taking place at Christie Park.
The two sides met most recently back in November and it was Paul Tisdale's side who ran out 2-0 victors at Stadium MK.
Click HERE for more Sky Bet odds, with up to 118 more odds available for this fixture.
ELSEWHERE IN SKY BET LEAGUE TWO!
Cambridge United v Crewe Alexandra
Carlisle United Notts County
Colchester United v Forest Green Rovers
Crawley Town v Mansfield Town
Lincoln City v Oldham Athletic
Macclesfield Town v Exeter City
Northampton Town v Newport County
Port Vale v Yeovil Town
Stevenage v Swindon Town
Tranmere Rovers v Grimsby Town
FOLLOW IT LIVE!
Tickets for tonight's clash remain on sale from MK Dons until midday. After this time, tickets will only be available at the Globe Arena. Tickets are priced at £21 adults, £17 seniors, £15 young persons/students and £6 under-18s while under-11s go FREE*.
Can't make the game? Supporters will be able to watch the match LIVE on iFollow MK Dons. To enjoy the live coverage on iFollow MK Dons, simply purchase a £10 Match Pass and then access the homepage shortly before kick-off - click HERE to purchase your Match Pass (£10) for the match.
Supporters outside the UK and Ireland will also be able to watch the action on iFollow MK Dons via either a Match Pass or Season Pass (£110 and provides provide access to watch up to 46 live MK Dons matches during the 2018/19 season) - click HERE for more information!
Supporters can also stay in touch with the action via mkdons.com’s Match Centre, which can be accessed by visiting the home page from 6pm.
There will also be full coverage on the Club’s social media channels – Twitter, Facebook, Instagram and Snapchat!
A full match report will be available to view on mkdons.com straight after the final whistle along with full reaction from Paul Tisdale and a player. Highlights will be available to view from midnight.