Dons manager Paul Ince drafts Frenchman Mathias Doumbe back into his starting eleven for the League 1 visit of Southampton.
Doumbe replaces Danny Woodards at right-back in the only change to the Dons side that has started the last three games.
On-loan Arsenal starlet Mark Randall retains his place in a three-man central midfield, meaning Irishman Stephen Gleeson remains on the bench, which also includes defender Darren Powell returning from a knee injury.
Southampton boss Alan Pardew makes two changes to the side that started Tuesday's home defeat to Swindon and they both come in defence.
Right-back Wayne Thomas misses out and is replaced by Joseph Mills, while Tunisian centre-half Radhi Jaidi is replaced by former Exeter defender Dan Seaborne.
Former Dons midfielder Jason Puncheon starts on the right wing, with Dean Hammond and Morgan Schneiderlin in the central positions.
MK DONS: Willy Gueret, Dean Lewington (c), Mathias Doumbe, David McCracken, Jermaine Easter, Aaron Wilbraham, Mark Carrington, James Tunnicliffe, Peter Leven, Luke Chadwick, Mark Randall.
SUBS: Stephen Gleeson, Lewis Gobern, Danny Woodards, Sol Davis, Luke Howell, Darren Powell, Dean Morgan.
SOUTHAMPTON: Kelvin Davis, Jose Fonte, Dan Harding, Jason Puncheon, Dean Hammond (c), Adam Lallana, Morgan Schneiderlin, Daniel Seaborne, Rickie Lambert, Joseph Mills, Lee Barnard.
SUBS: Bartosz Bialkowski, Paul Wotton, Chris Perry, Papa Waigo N'Diaye, David Connolly, Lloyd James, Alex Oxlade-Chamberlain.
REFEREE: Colin Webster (Tyne and Wear)
