Dons manager Paul Ince makes three changes to his side for the League 1 trip to Southampton, returning to a 4-5-1 formation at St Mary's Stadium.
Illness keeps Aaron Wilbraham out of the starting eleven so Jermaine Easter will lead the line on his own, supported by Jason Puncheon in the hole. In midfield, Jemal Johnson comes in on the left flank and Lewis Gobern replaces Aaron Doran on the right.
The final change comes in defence, where Darren Powell returns to fitness to take his central place alongside David McCracken, with Mathias Doumbe switching to right-back.
Southampton boss Alan Pardew names an unchanged side from last Saturday's win over Oldham, with former Wimbledon 'keeper Kelvin Davis between the sticks and £1 million Rickie Lambert leading the line in attack.
There is no place in the Southampton 18 for midfielder Oscar Gobern, who returned to St Mary's last week after a month on loan with the Dons.
SOUTHAMPTON: Kelvin Davis (c), Lloyd James, Radhi Jaidi, Neal Trotman, Dan Harding, Paul Wotton, Dean Hammond, Morgan Schneiderlin, Adam Lallana, Rickie Lambert, Papa Waigo N'Diyae.
SUBS: Bartosz Bialkowski, Wayne Thomas, Chris Perry, Joseph Mills, Jacob Mellis, Michail Antonio, David Connolly.
MK DONS: Willy Gueret, Dean Lewington (c), Mathias Doumbe, David McCracken, Stephen Gleeson, Jermaine Easter, Jemal Johnson, Lewis Gobern, Jason Puncheon, Peter Leven, Darren Powell.
SUBS: Aaron Wilbraham, Sam Baldock, Stuart Searle, Sol Davis, Luke Howell, Danny Swailes, Aaron Doran.
REFEREE: Mick Russell (Hertfordshire)
