The Dons booked their place in the Last 16 with a thrilling 4-2 victory over Premier League side Queens Park Rangers at Loftus Road on Saturday afternoon, in their first ever fourth round tie.
The draw will take place at Wembley Stadium live on ITV1 and mkdons.com will have the latest on who the Dons will face on the weekend of the 16th and 17th February.
Having beaten Cambridge City, AFC Wimbledon, Sheffield Wednesday and QPR to get to the fifth round the Dons will be hoping for another headline-making tie.
The draw numbers:
1 Luton Town
2 Oldham Athletic or Liverpool
3 Wigan Athletic
4 Blackburn Rovers
8 Leeds United or Tottenham Hotspur
10 Manchester City
11 Manchester United or Fulham
12 Brentford or Chelsea
14 Huddersfield Town or Leicester City
15 Milton Keynes Dons